Inhalation Exposure Systems
Overview: FLOOR MODEL IES
The Inhalation Exposure System provides reproducible animalexposure to droplet-borne contaminants and infectious agents. Italso produces deep-lung infections that more closely simulatereal-world circumstances.
The system allows you to vary the concentration of airbornepathogens, the rate of air flow, and the length of exposure, soexperiments can be reproduced accurately and adjusted easily. UVlamp (254nm), HEPA filter (0.3um) and an air incinerator fordecontamination provide additional protection in the lab.
The system is a top loading whole-body exposure chamber for thequantitative experimental infection of animals by inhalation of airbearing the pathogenic agent. The heart of the system is thenebulizer-venturi unit into which the suspension is introduced. Airunder pressure atomizes the suspension, which is mixed withfiltered room air drawn into the system by suction beyond thedecontamination system. By varying the number of micro-organisms inthe suspension, the proportion of bacteria-bearing nuclei can bevaried. The system permits control of the volume of air movingthrough the chamber per unit time.
The animals are placed in a (5) compartmented mesh stainlesssteel basket within the chamber. Compressed air and vacuum pump,along with the necessary controls and flow indicators, are builtinto the system. A programmable control is used to time: preheat,nebulizing, cloud decay, and decontamination periods.
This Inhalation Exposure System provides whole-body exposure forapproximately 100 mice.
New features include sensors to monitor flow within the chamber,incinerator performance, system timers for filters and UV, plus 5recipe creation files.
